This book documents possibilities and challenges associated with using Problem-Based Learning (PBL) strategies nationally and internationally. The authors draw on experiences and research from their specific educational contexts and fields. Discussing and choosing teaching and learning methodologies at universities is related to questions about the role of universities in the knowledge production process. These are questions that we find important to discuss at each level of the universities´ organizational hierarchies in order to meet the challenges of educating academics for future workplaces. A related question is: How do we meet those challenges? At Aalborg University, one of the solutions is the use of the PBL methodology and principles as they have been developed within the Danish educational context. Aalborg University constitutes a specific context for practicing PBL. As will become apparent from the contributions in this book, each university represents a specific and unique context for teaching and learning. Consequently, there are many aspects to consider if a university chooses to implement PBL methodologies. These include the specific societal and cultural conditions for practicing PBL, specific subject areas, students´ diverse backgrounds, and the teachers’ qualifications.