Methods and Applications of Sample Size Calculation and Recalculation in Clinical Trials (Bog, Hardback, Engelsk)

Methods and Applications of Sample Size Calculation and Recalculation in Clinical Trials (Bog, Hardback, Engelsk)

Af: Meinhard Kieser


Forlag: Springer Nature Switzerland AG

  • Type: Bog
  • Format: Hardback
  • Sprog: Engelsk Sprog: Engelsk
  • ISBN-13: 9783030495275
  • Udgave: 1st ed. 2020
  • Udgivelsesdato: 20-11-2020
  • Første udgivelsesår: 2020
  • Serie: Springer Series in Pharmaceutical Statistics
  • Illustrationer: 126 Illustrations, black and white; XIV, 396 p. 126 illus.
  • Originalsprog: Switzerland
  • Sideantal: 396
  • Indbinding: Hardback
  • Forlag: Springer Nature Switzerland AG
  • Sideoplysninger: 396 pages, 126 Illustrations, black and white; XIV, 396 p. 126 illus.
  • Mål: 162 x 241 x 32

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Beskrivelse

This book provides an extensive overview of the principles and methods of sample size calculation and recalculation in clinical trials. Blinded sample size recalculation procedures for internal pilot study designs are considered, as well as methods for sample size reassessment in adaptive designs that use unblinded data from interim analyses.

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