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The second edition of the book therefore considerably expands with the addition of three new chapters relating to Bayesian models, Generalized linear and nonlinear mixed effects models, and Principles of simulation.
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This is a well thought-out, highly practical text covering contemporary 'in vitro' techniques for drug absorption studies. Starting at the... Læs mere
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This book examines the available information on the structure of the RNA binding STAR domain and provides insights into how these proteins discriminate between different RNA targets. It reviews what is known about STAR proteins and human disease.
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Bioinformation Discovery illustrates the power of biological data in knowledge discovery. It describes biological data types and representations... Læs mere
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Some human populations escaped tropical infections by migrating into cold climates but then had to procure fuel, warm clothing, durable housing, and... Læs mere
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This book approaches the subject from a mechanistic perspective that pitches the language at a level that is understandable to those entering the field and who are not familiar with its common phrases or complex terms.
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Beads made from Egyptian faience have been excavated from grave deposits (c. In the meantime, the use of water-soluble hydrocolloid beads... Læs mere
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This book assesses techniques used in therapeutic development across the product lifecycle from early discovery through expression and purification, large scale production, formulation development, lot-to-lot comparability studies, commercial support and more.
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Optimum quality data facilitate optimum quality statistical analysis and interpretation of the results obtained, which in turn... Læs mere
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At the moment, there is no dedicated book to summarize the roles, the significance, and potential therapeutic targeting of transcriptional factors from the perspective of signaling cascade, and thus, directly impacting the functionality of transcriptional factors in cancer.
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In Vitro Toxicology Systems brings together important issues and considerations needed in order to develop a workable, reliable, integrated testing strategy for the replacement of animals in toxicity testing regimes.
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Genotoxicity and DNA Repair: A Practical Approach provides a key reference for determining how to analyze the genotoxic activity of molecules or materials and, at the same time, serves as a useful tool for researchers in the Environmental Mutagenesis and DNA Repair fields.