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Using the Methods in Molecular Biology(TM) format, this book covers key areas in food safety: detection of low level chemical residues, pesticide analysis using chromatographic techniques, and the revealing of mycotoxins and chemical contaminants in packaging.
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In Systems Biology in Drug Discovery and Development: Methods and Protocols, leading experts provide a practical, state-of-the-art, and holistic view of the translation of systems biology into better drug discovery and personalized medical practice.
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Adverse drug reactions and interactions remain a major healthcare issue. This fully updated and revised new edition of the indispensible guide to drug interactions includes fresh research on pharmacogenomics as well as an expanded section on illicit drugs.
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This volume includes work by leading experts who provide an in-depth view of key protocols used in drug discovery laboratories. It covers both classic and cutting-edge techniques and provides reproducible laboratory protocols and troubleshooting tips.
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In Vitro Neurotoxicology: Methods and Protocols presents a series of cellular, biochemical, and molecular methodological protocols in the area of in vitro neurotoxicology. Features key tips and advice, there is emphasis on mammalian cell culture systems.
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This Methods in Molecular Biology(TM) book addresses special considerations when applying toxicity studies to nanomaterials and details new methods for the study of nanotoxicity. Includes materials lists, step-by-step lab protocols, troubleshooting tips and more.
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This Methods in Molecular Biology(TM) book details rational drug design, including virtual screening of chemical hits, lead discovery by high throughput screening, combinatorial and fragment based lead generation, peptide based drug discovery and animal models.
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Emphasizing the newest developments in the field, this volume presents detailed methods with added emphasis on therapeutic protein discovery. It features key tips and valuable implementation advice to ensure successful results.
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Vital to academic researchers, the medical field, and especially to biotech and pharmaceutical scientists, metabolomics is a rapidly expanding field that will provide a key link between functional biology (phenotypes) and the inner workings of cells in tissues or whole organisms.
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In Functional Selectivity of G Protein-Coupled Receptors expert neuroscientists and pharmacologists review the work that demonstrated the existence of functional selectivity, placed it within a theoretical framework, and provided a mechanistic basis for the phenomenon.
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With its versatility, ease of use and similarity to the human genome, the mouse has become a top model for medical study. This book provides background of mice as models and details a collection of techniques for a wide variety of specific disease topics.