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This book offers an update on the molecular genetics of pancreatic cancer development and progression, covering familial and sporadic pancreatic cancer, molecular pathology, K-Ras signaling, mouse models, epigenetics and translational implications.
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In Statistical Methods for Microarray Data Analysis: Methods and Protocols, expert researchers in the field detail many methods and techniques used to study microarrays, guiding the reader from microarray technology to statistical problems of specific multivariate data analysis.
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Protein expression in a heterologous host is a cornerstone of biomedical research and of the biotechnology industry. For example, membrane... Læs mere
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Evaluating potential mutagenic activity is a critical step in assessing the safety of both new and pre-existing chemical types. In this book, expert contributors help to satisfy the demand for education in this vitally important field of research.
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The rapid progression of genetics and molecular biology has turned chromosomal engineering from science fiction to reality, with the successful... Læs mere
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Classical methods for microbial strain engineering, used to improve the production of bioproducts, have serious drawbacks and have been found to be unsuitable for complex strain development applications.
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This book examines developments in statistical methodology and the challenges that followed rapidly improving sequencing technologies. Includes articles encompassing theoretical works and hands-on tutorials, as well as many reviews with key biological insight.
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The 2nd edition of this Methods in Molecular Biology(TM) volume provides novel approaches inspired by Xenopus tropicalis and the sequencing of its genome. Offers a toolkit enabling laboratories to maximize the power of this extraordinary experimental system.
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This Methods in Molecular Biology(TM) book covers mRNA synthesis, modifications and delivery, offering protocols, material lists and practical tips along with examples of cell reprogramming and analysis in the fields of immunotherapy and stem cell research.
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Written in the popular Methods in Molecular Biology(TM) series format, this book presents a collection of techniques aimed at bridging the translational gap in muscle gene therapy between the prevalent rodent models and vitally important larger animal models.