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This book offers an update on the molecular genetics of pancreatic cancer development and progression, covering familial and sporadic pancreatic cancer, molecular pathology, K-Ras signaling, mouse models, epigenetics and translational implications.
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Rb and Tumorigenesis examines how recent advances have demonstrated the interaction of Rb with chromatin remodeling enzymes. This new title explores the potential roles of these... Læs mere
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This volume offers an analysis of the scale and nature of the immunological issues facing regenerative medicine, drawing on the expertise of... Læs mere
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This book is essential reading for all researchers, biochemists and crystallographers working with membrane proteins, who are interested by the... Læs mere
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Understanding Biology Using Peptides: Proceedings of the 19th American Peptide Symposium highlights many of the recent developments in peptide science, with a particular emphasis on how these advances are being applied to basic problems in biology and medicine.
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Research has revealed that natural killer (NK) cells are sentinels of the innate immune response. This text offers detailed protocols plus the latest methods and techniques designed to study NK cells within specialized tissue sites in both mice and humans.
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Here, leading researchers describe the latest techniques for investigating the mechanisms underlying transcription factor nuclear-cytoplasmic trafficking, as well as the functional impact of post-translational modifications on transcription factor function.
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This authoritative book emphasizes the molecular effects of protein misfolding at a cellular level, a vital subject. It aims to pinpoint possible manipulations and treatment strategies that can counteract, modify, or delay the consequences of misfolding.
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Human pluripotent stem cells, including human embryonic stem cells and induced pluripotent stem cells, are a key focus of current biomedical research.
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Focusing on Systems of ODEs, parameterization of signaling models, signaling pathways, mass-action kinetics and ODEs and how to use modeling to plan experiments, this Methods in Molecular Biology(TM) book details steps for getting optimal laboratory results.
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In Embryo Culture: Methods and Protocols, expert researchers in the field detail many of the methods which are now commonly used to study human embryo culture.
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Exploring the activation and function of components of the MAPK signaling cascades, this volume presents fully updated techniques to study MAPK. Chapters include lists of... Læs mere