This Methods in Molecular Biology(TM) book reviews methods and techniques used for exon skipping, such as methods on how to distinguish "real polymorphisms" from mutations that affect splicing. Includes protocols, materials lists, pitfalls and troubleshooting tips.
This book introduces DIGE and its advantages in quantitative protein analysis, providing detailed protocols and important notes on the practical aspects of DIGE with both generic and specific applications in the various areas of Quantitative Proteomics.
The epigenetic regulation plays an important role in normal development and maintenance of tissue specific genes expression in humans and the disturbance of these patterns lead to changes involved in tumor formation.
This comprehensive new resource in Springer's Methods in Molecular Biology series features contributions from leading researchers who provide expert advice and reproducible, cutting-edge protocols for examining glycoproteins through mass spectrometry.
This Methods in Molecular Biology(TM) book covers knowledge dissemination and theoretical assessment of OR structure and function, plus development and use of expression systems and experimental functional analysis. Offers reproducible protocols, tips and more.
Androgen Action provides a tool box to study various phases of androgen action, from its entry to the cell, to the phenotypic response that the cell mounts. The... Læs mere
This Methods in Molecular Biology(TM) volume details methods for fabricating DNA, including techniques for the assembly of oligonucleotide, cloning of synthons into larger fragments, protocols, software and educational and biosecurity impacts of gene synthesis.
In DNA Damage Detection In Situ, Ex Vivo, and In Vivo: Methods and Protocols, expert researchers explore the latest advances in the... Læs mere
This book offers basic technical information on controlled genetic manipulation, with examples of creative implementation of the methodology. Covers use of Cre-recombinase, methods for introducing genetic material into the brain, use of optogenetics and more.
The field of protein NMR spectroscopy has rapidly expanded into new areas of biochemistry, molecular biology and cell biology research that were impossible to study as recently as ten years ago.
This Methods in Molecular Biology(TM) volume offers detailed protocols, with theoretical background, and step-by-step instructions on implementing synchronization, as well as current techniques for the enhanced study of regulatory mechanisms in cell cycle events.
Systems biology is the study of interactions between assorted components of biological systems with the aim of acquiring new insights into how organisms function and respond to different stimuli.