Neurodegeneration tackles the challenges involved with neurodegenerative disorders, such as Alzheimer's and Parkinson's disease. The text presents cutting-edge analytical and technological approaches to study the mechanisms underlying neurodegenerative processes.
Forensic DNA profiling procedures are mainly based on high resolution and high throughput capillary electrophoresis separation and detection systems of PCR amplicons obtained from DNA genomic markers with different inheritance patterns.
The rapid pace of microRNA (miRNA) research continues to drive the advances of techniques for miRNA expression profiling,... Læs mere
This Methods in Molecular Biology(TM) book shows how PARP proteins act in normal and pathogenic development of organisms, advances knowledge of developmental pathways regulation, and furthers development of new drugs and methods to target PARP-dependent processes.
This Methods in Molecular Biology(TM) volume offers methods for investigating chromatin remodeling in vitro and in vivo, in yeast, plants and mammalian cells, and at local and global levels. Includes materials lists, protocols, troubleshooting tips and more.
This Methods in Molecular Biology(TM) book covers microfluidic device fabrication, on-chip sample preparation, diagnostic applications and detection methods from basic fabrication methods to commercializing research. Includes materials, protocols, tips and more.
This selection of protocols and procedures includes the latest techniques and shows how to make use of cellular, tissue, and whole animal models which can then be applied to the investigation of neurotrophic factors and other agents impacting on these systems.
In mTOR: Methods and Protocols expert researchers in the field detail many of the methods which are now commonly used to study mTOR. These include methods and techniques used... Læs mere
The discipline of developmental toxicology is an integration of concepts, models, and methodologies based heavily on the superimposition of toxicology principles upon the science of developmental biology.
This Methods in Molecular Biology(TM) book reviews methods and techniques used for exon skipping, such as methods on how to distinguish "real polymorphisms" from mutations that affect splicing. Includes protocols, materials lists, pitfalls and troubleshooting tips.
This book introduces DIGE and its advantages in quantitative protein analysis, providing detailed protocols and important notes on the practical aspects of DIGE with both generic and specific applications in the various areas of Quantitative Proteomics.
The epigenetic regulation plays an important role in normal development and maintenance of tissue specific genes expression in humans and the disturbance of these patterns lead to changes involved in tumor formation.