This authoritative book emphasizes the molecular effects of protein misfolding at a cellular level, a vital subject. It aims to pinpoint possible manipulations and treatment strategies that can counteract, modify, or delay the consequences of misfolding.
Evaluating potential mutagenic activity is a critical step in assessing the safety of both new and pre-existing chemical types. In this book, expert contributors help to satisfy the demand for education in this vitally important field of research.
Protein expression in a heterologous host is a cornerstone of biomedical research and of the biotechnology industry. For example, membrane... Læs mere
Here, leading researchers describe the latest techniques for investigating the mechanisms underlying transcription factor nuclear-cytoplasmic trafficking, as well as the functional impact of post-translational modifications on transcription factor function.
National Institute of Allergy and Infectious Diseases, NIH: Volume 2: Impact on Global Health covers the scientific aspects of the entire portfolio of NIAID, including microbiology and infectious disease, HIV/AIDS, and immunology and vaccines.
With significant developments in the areas of chromatography and spectroscopy as well as the unique inherent chemical diversity of natural products, vital in drug research, natural products research has gained new momentum.
This cutting-edge book delivers invaluable guidance to new and experienced laboratory researchers delving into the sophisticated study of the kidney. It includes step-by-step instructions providing a level of detail rarely found in journal articles.
As our understanding of G protein-coupled receptor (GPCR) signal transduction continues to grow, we cannot help but be struck by the emerging complexity and the ability of this receptor superfamily to continually surprise us as new facets are discovered.
Research has revealed that natural killer (NK) cells are sentinels of the innate immune response. This text offers detailed protocols plus the latest methods and techniques designed to study NK cells within specialized tissue sites in both mice and humans.
In its new edition, this Methods in Molecular Biology(TM) book offers protocols for preparing amyloid and its precursors, cell culture models, extraction from tissue, detection in vitro and in vivo and nontransgenic methods for developing amyloid mouse models.
Reflecting a vast amount of new information concerning the functional characteristics of the various 5-HT receptor subtypes and the Na+-dependent serotonin transporter... Læs mere
Biomedical Literature Mining, discusses the multiple facets of modern biomedical literature mining and its many applications in genomics and systems biology.