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In this volume, the specific challenges and problems facing the evaluation of new oncology agents are explored with regards to pharmacokinetic, pharmacodynamic modeling and clinical pharmacology development strategies.
This book introduces the reader to a new method of data assimilation with deterministic constraints (exact satisfaction of dynamic... Læs mere
This book presents a collection of results from the interdisciplinary research project “ELLI” published by researchers at RWTH Aachen University, the TU Dortmund and Ruhr-Universität Bochum between 2011 and 2016.
This book provides a comprehensive view of metabolomics, from the basic concepts, through sample preparation and analytical methodologies, to data interpretation and applications in medicine.
Building on the author’s earlier Applied Simulation and Optimization, this book presents novel methods for solving problems in industry, based on hybrid simulation-optimization approaches that combine the advantages of both paradigms.
Mathematical models in biology and medicine cannot be based on natural laws as it is the case with physics and chemistry. In general, several... Læs mere
Proceedings of the FISITA 2012 World Automotive Congress are selected from nearly 2,000 papers submitted... Læs mere
The five-volume set LNCS 7971-7975 constitutes the refereed proceedings of the 13th International Conference on Computational Science and Its Applications, ICCSA 2013, held in Ho Chi Minh City, Vietnam, in June 2013.