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This text is for advanced undergraduates of microbiology and medical microbiology, presenting a comprehensive introduction to late-1990s molecular biology of the interactions between bacteria and eukaryotic cells, and their relevance to human diseases.
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The past 25 years has seen the emergence of a wealth of data suggesting that novel biological functions of known proteins play important roles in biology and medicine. This ability of proteins to exhibit more than one unique biological activity is known as protein moonlighting.
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Microbiota-associated pathology can be a direct result of changes in general bacterial composition, such as might be found in periodontitis and bacterial vaginosis, and/or as the result of colonization and/or overgrowth of so called keystone species.