New pathways have been discovered and expanded our knowledge of the ways in which genes and gene products affect bone cells and thereby bone mass and bone strength.
PCR methods for the detection of microbial pathogens have made relatively little impact in diagnostic microbiology laboratories due to the common decision to use... Læs mere
During the past decade, remarkable progress has been made in the development of newer drugs to prevent and treat thromboembolic disorders, such as oral direct anti-Xa and anti-IIa antagonists, as well as oral antiplatelet ADP antagonists with rapid onset and offset.
In this book, researchers update the classic methods and introduce new approaches that go beyond basic conjugation techniques. There is emphasis on the interplay of organic synthesis, molecular biology, surface biotechnology and biomaterials engineering.
In its revised second edition, this Methods in Molecular Biology(TM) book provides advanced techniques and animal models that are critical for integrated pain research. Includes materials and reagents lists, reproducible lab protocols and troubleshooting tips.
The past 30 years have seen the emergence of a growing desire worldwide that positive actions be taken to restore and protect the environment from the degrading effects of all forms of pollution – air, water, soil, and noise.
In this book, expert researchers provide a number of methods for the culture of a range of specific cells and tissues isolated from the key genetic model of the fetal or adult mouse. Notes provide practical, straight-from-the-lab knowledge and experiences.
Laser microdissection techniques have revolutionized the ability of researchers in general, and pathologists in particular, to carry out molecular... Læs mere
The 2nd edition of this Methods in Molecular Biology(TM) book offers methods for investigating production and analysis of transgenic plants, focused on selection and detection methods, transformation technology, targeting, silencing and directed mutation and more.
International biobank collaborations allow for studies with large number of subjects where generalizability of findings across populations can be investigated, which means... Læs mere
Since the publication of the popular first edition, genomic methods have become more accessible, allowing antibiotic researchers to probe not only the sequence of antibiotic resistance determinants but the mechanism whereby they are expressed and regulated.
Another key addition to Springer's Methods in Molecular Biology series, this volume includes methods for direct biolistic transfection of DNA using ballistic devices such as a gene gun. Lab-ready protocols and expert troubleshooting guarantee reproducibility.