The discovery of catalytic RNAs in the mid-1980s marked the beginning of a new era in RNA biology and an ever increasing appreciation of the diverse and critical roles played by this fascinating molecule.
This book provides an overview of single-molecule approaches applied to biomolecules, including a solid introduction to the most widely used single-molecule techniques. It features readily reproducible laboratory protocols and notes on troubleshooting.
Part of the respected Methods in Molecular Biology(TM) series, this practical volume features brief introductions to the key topics, lists the necessary materials and reagents, and includes reproducible laboratory protocols as well as key troubleshooting tips.
Here is a collection of protocols for the analysis of viral small RNAs and natural antiviral RNAi responses as well as for development and optimization of RNAi-based antiviral drugs. The methods here can also be applied outside the context of a virus infection.
This volume includes work by leading experts who provide an in-depth view of key protocols used in drug discovery laboratories. It covers both classic and cutting-edge techniques and provides reproducible laboratory protocols and troubleshooting tips.
Adverse drug reactions and interactions remain a major healthcare issue. This fully updated and revised new edition of the indispensible guide to drug interactions includes fresh research on pharmacogenomics as well as an expanded section on illicit drugs.
This volume in the Methods in Molecular Biology(TM) series presents established and emerging methods for the application of oligonucleotides as therapeutics. Includes protocols for optimizing cell uptake, assaying gene knockdown, target site selection and more.
Sections of the book are dedicated to state-of-the art techniques which enable investigation of uracil insertion/deletion RNA editing in mitochondrion of... Læs mere
This book assembles experts from many fields to provide a practical overview of biomedical nanotechnology, from the conception of novel materials in the lab to their application in the clinic. Includes case studies, regulatory and patent information and more.
Focusing on differential analysis and protein modifications, Gel-Free Proteomics addresses contemporary methods for gel-free proteome research. The text describes the vital procedures needed to perform gel-free proteomics.
Fungal Genomics explores the three most likely fronts upon which the field will advance: the sequencing of more fungal genomes, the mining of sequenced genomes for useful information, and the use of genomics sequences to explain biological processes.
At the intersection of metabolite analysis, metabolic fingerprinting, and metabolomics, the study of metabolic profiling has evolved steadily over the course of time as have the methods and technologies involved in its study.