This comprehensive volume covers techniques for the study of platelet function, approaches for investigating megakaryocyte function, and perspectives on important overall concepts in the field of megakaryocyte and platelet biology.
Since the initial discovery of the claudins, the field of tight junctions and cell polarity has become increasingly energized, mainly due to the fact that the claudins... Læs mere
Recent years have seen significant advances in technologies that enable us to analyze transcription factors, a pivotal cell regulatory process in plants. This comprehensive survey covers the basic concepts as well as detailed protocols of tools to study TFs.
This book offers an in-depth overview of the methods that have been applied to studying the nitrogenase at a molecular level, ranging from genetic, biochemical, spectroscopic and chemical methods to theoretical calculations.
The volume delves into vital subjects such as neoplasia studies with animal models and human patients, therapeutic roles for polyamine inhibitors and analogs, polyamine... Læs mere
This timely and authoritative book aims to provide a comprehensive toolkit to study gene regulatory networks from the point of data generation to processing, visualization, and modeling. The book is intended for novices and experienced researchers alike.
Increasing interest in mitochondrial bioenergetics is being driven by the impact of drug and environmental chemical-induced disturbances of mitochondrial function as well as hereditary deficiencies and the progressive deterioration of bioenergetic performance with age.
This book presents methods and protocols for both fixed and live cells from everything from bacteria to mammalian models, offering detailed techniques from experts in the field. The text includes vital notes on troubleshooting and avoiding known pitfalls.
Over the last two decades advances in genotyping technology, and the development of quantitative genetic analytical techniques have made it possible to... Læs mere
The discovery of catalytic RNAs in the mid-1980s marked the beginning of a new era in RNA biology and an ever increasing appreciation of the diverse and critical roles played by this fascinating molecule.
This book provides an overview of single-molecule approaches applied to biomolecules, including a solid introduction to the most widely used single-molecule techniques. It features readily reproducible laboratory protocols and notes on troubleshooting.
Part of the respected Methods in Molecular Biology(TM) series, this practical volume features brief introductions to the key topics, lists the necessary materials and reagents, and includes reproducible laboratory protocols as well as key troubleshooting tips.