Here is a collection of protocols for the analysis of viral small RNAs and natural antiviral RNAi responses as well as for development and optimization of RNAi-based antiviral drugs. The methods here can also be applied outside the context of a virus infection.
This volume includes work by leading experts who provide an in-depth view of key protocols used in drug discovery laboratories. It covers both classic and cutting-edge techniques and provides reproducible laboratory protocols and troubleshooting tips.
Adverse drug reactions and interactions remain a major healthcare issue. This fully updated and revised new edition of the indispensible guide to drug interactions includes fresh research on pharmacogenomics as well as an expanded section on illicit drugs.
This volume in the Methods in Molecular Biology(TM) series presents established and emerging methods for the application of oligonucleotides as therapeutics. Includes protocols for optimizing cell uptake, assaying gene knockdown, target site selection and more.
Sections of the book are dedicated to state-of-the art techniques which enable investigation of uracil insertion/deletion RNA editing in mitochondrion of... Læs mere
This book assembles experts from many fields to provide a practical overview of biomedical nanotechnology, from the conception of novel materials in the lab to their application in the clinic. Includes case studies, regulatory and patent information and more.
Focusing on differential analysis and protein modifications, Gel-Free Proteomics addresses contemporary methods for gel-free proteome research. The text describes the vital procedures needed to perform gel-free proteomics.
Fungal Genomics explores the three most likely fronts upon which the field will advance: the sequencing of more fungal genomes, the mining of sequenced genomes for useful information, and the use of genomics sequences to explain biological processes.
At the intersection of metabolite analysis, metabolic fingerprinting, and metabolomics, the study of metabolic profiling has evolved steadily over the course of time as have the methods and technologies involved in its study.
The aim of Two Hybrid Technologies: Methods and Protocols is to provide a compendium of state-of-the art protocols for the investigation of binary PPIs with the classical yeast two-hybrid (Y2H) approach, Y2H variants and other in vivo methods for PPI mapping.
“Recent studies have discovered new known and characterized cytokines, allowing for advancement in miniaturization of micro-analytical methods as well as the extensive development of bio-informatics and nanotechnology.
Research into nanopores holds out the promise of ultrafast--and cheaper--DNA sequencing. This study sets out the molecule characterization techniques now available in the field, with numerous step-by-step protocols and expert troubleshooting advice.